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Article

Notch signalling governs human enteric nervous system progenitor dynamics

2026-05-04

Abstract excerpt

<h4>ABSTRACT</h4> The enteric nervous system (ENS) is the main branch of the peripheral nervous system that innervates the gastrointestinal tract controlling vital functions. It arises during embryogenesis via migration and differentiation of neural crest-derived ENS progenitors. Perturbation of these processes, caused by mutations in key signalling pathway components and transcription factors, prevents progenito...

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Literature Corpus work
d8a5b368-c088-5c94-868e-0227f8d0cc1c
DOI
10.64898/2026.05.01.722150
Open publication

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