Role of Folate Functionalized Human Serum Albumin Nano-formulation for Bleomycin Delivery on Gene Expression in Gastric Cancer Cells

Abstract excerpt

<title>Abstract</title> <p>Nanoparticles (NPs) are considered an effective and accurate approach for targeted drug delivery. This research focuses on the modification of human serum albumin (HSA) using folic acid (FA) to enhance the targeted delivery of bleomycin (BLM) to gastric cancer cells. The structure and properties of FA-HSA-BLM formulated nanoparticles were effectively analyzed. The methods utilized inclu...

Topics

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• Curcumin's Biomedical Applications
• Folate and B Vitamins Research
• Protein purification and stability
• Tannin, Tannase and Anticancer Activities
• Tea Polyphenols and Effects

Identifiers and source

Literature Corpus work

a2efb4e0-ed5c-548b-8ee2-4286578a8b65

DOI

10.21203/rs.3.rs-6742375/v1