Article

Using Artificial Intelligence to Assess Treatment-Effect Heterogeneity in Pragmatic Cardiovascular Trials: Insights from TRANSFORM-HF

2026-01-19

Abstract excerpt

<h4>Background and Aims</h4> Pragmatic clinical trials are designed to assess interventions in real-world settings, and their broad inclusion criteria and clinical variability create valuable opportunities for exploring heterogeneity of treatment effects. In this context, TRANSFORM-HF was a pragmatic trial that found no overall survival difference between torsemide and furosemide in patients hospitalized with hea...

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Literature Corpus work: d88019fb-2e63-515a-8c4f-4842d86153bf
DOI: 10.64898/2026.01.16.26344310

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