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Comparative Efficacy and Safety of Direct Oral Anticoagulants in Atrial Fibrillation and Heart Failure: A Bayesian Network Meta-Analysis of Reconstructed IPD and RMST

2026-06-14

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<title>Abstract</title> <p> Purpose To determine the optimal direct oral anticoagulant (DOAC) for patients with atrial fibrillation (AF) and heart failure (HF) by evaluating absolute comparative efficacy and safety using reconstructed individual patient data (IPD) and restricted mean survival time (RMST). Methods HF subgroup data from four landmark DOAC trials (N = 25,762) were extracted. Pseudo-IPD were algor...

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Literature Corpus work
d1655183-be3b-5360-9c4e-fb449392066a
DOI
10.21203/rs.3.rs-10002222/v1
Open publication

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Comparative Efficacy and Safety of Direct Oral Anticoagulants in Atrial Fibrillation and Heart Failure: A Bayesian Network Meta-Analysis of Reconstructed IPD and RMSTDOI 10.21203/rs.3.rs-10002222/v1
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