Back to search

Article

The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia

2021-10-01

Abstract excerpt

Tumor suppressor genes are highly affected during the development of leukemia, including circadian clock genes. Circadian rhythms constitute an evolutionary molecular machinery involving many genes, such as BMAL1, CLOCK, CRY1, CRY2, PER1, PER2, REV-ERBa, and RORA, for tracking time and optimizing daily life during day-night cycles and seasonal changes. For circulating blood cells many of these genes coordinate the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d7d317ce-5765-5d78-b405-ca94eaae3c6c
DOI
10.1080/10643389.2021.1985882
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemiaDOI 10.1080/10643389.2021.1985882
Environmental and genetic risk factors for childhood leukemia: appraising the evidence.Semantic proximity
Breast Cancer ExposomicsSemantic proximity
Circadian Rhythm Disruption in Cancer BiologySemantic proximity
Benzene exposure is associated with epigenetic changes (Review)Semantic proximity
Aryl hydrocarbon receptor–kynurenine axis promotes oncogenic activity in BCP-ALLSemantic proximity
Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying MechanismsSemantic proximity
Benzo(a)pyrene and Cerium Dioxide Nanoparticles in Co-Exposure Impair Human Trophoblast Cell Stress SignalingSemantic proximity
Epigenetic Effects of Benzene in Hematologic Neoplasms: The Altered Gene ExpressionSemantic proximity
Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessmentSemantic proximity
Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising BiomarkersSemantic proximity
The circadian clock circuitry and the AHR signaling pathway in physiology and pathology.Semantic proximity
Carcinogenic effects of circadian disruption: an epigenetic viewpointSemantic proximity
Select a neighboring publication to make it the new centre.