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Article

Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms

29 Mar 2016

Abstract excerpt

Leukemia is the most common cancer in children, representing 30% of all childhood cancers. The disease arises from recurrent genetic insults that block differentiation of hematopoietic stem and/or progenitor cells (HSPCs) and drives uncontrolled proliferation and survival of the differentiation-blocked clone. Pediatric leukemia is phenotypically and genetically heterogeneous with an obscure etiology. The...

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PMID: 27043530
DOI: 10.3390/ijms17040461

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