Article

Integration of single-cell RNA-seq data into metabolic models to characterize tumour cell populations

2018-01-30

Abstract excerpt

<h4>Motivation</h4> Metabolic reprogramming is a general feature of cancer cells. Regrettably, the comprehensive quantification of metabolites in biological specimens does not promptly translate into knowledge on the utilization of metabolic pathways. Computational models hold the promise to bridge this gap, by estimating fluxes across metabolic pathways. Yet they currently portray the average behavior of intermi...

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Literature Corpus work: d751fd69-f70c-5b39-a709-0f22c264e713
DOI: 10.1101/256644

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