Article

Identification and analysis of splicing quantitative trait loci across multiple tissues in the human genome

2020-05-30

Abstract excerpt

We have developed an efficient and reproducible pipeline for the discovery of genetic variants affecting splicing (sQTLs), based on an approach that captures the intrinsically multivariate nature of this phenomenon. We employed it to analyze the multi-tissue transcriptome GTEx dataset, generating a comprehensive catalogue of sQTLs in the human genome. A core set of these sQTLs is shared across multiple tissues. Do...

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Literature Corpus work: d284ea69-86c4-5845-8ef0-0e32f5bad387
DOI: 10.1101/2020.05.29.123703

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