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Shared Genetic Architecture between Muscle and Bone: Identification and Functional Implications of <i>EPDR1</i> , <i>PKDCC</i> , and <i>SPTBN1</i>

2023-05-15

Abstract excerpt

Recent studies suggest a shared genetic architecture between muscle and bone, yet the underlying molecular mechanisms remain elusive. This study aims to identify the functionally annotated genes with shared genetic architecture between muscle and bone using the most up-to-date genome-wide association study (GWAS) summary statistics from bone mineral density (BMD) and fracture-related genetic variants. We employed...

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Literature Corpus work
d6a07af0-4f7e-59f6-9eac-7d7e5043c24d
DOI
10.1101/2023.05.14.540743
Open publication

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Shared Genetic Architecture between Muscle and Bone: Identification and Functional Implications of <i>EPDR1</i> , <i>PKDCC</i> , and <i>SPTBN1</i>DOI 10.1101/2023.05.14.540743
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