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Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

2023-07-19

Abstract excerpt

<title>Abstract</title> <p>Background Abdominal obesity is appreciated as a major player in insulin resistance and metabolically dysfunctional adipose tissue. Inappropriate extracellular matrix (ECM) remodeling and functional alterations in human adipose stromal/stem cells (hASCs) have been linked with visceral white adipose tissue (vWAT) dysfunction in obesity. Understanding the interactions between hASCs and t...

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Literature Corpus work
d678f7db-0fcb-5cef-80fd-fc85cb93d077
DOI
10.21203/rs.3.rs-2437381/v1
Open publication

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Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissueDOI 10.21203/rs.3.rs-2437381/v1
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