Article

The UBAP2L ortholog PQN-59 contributes to stress granule assembly and development in <i>C. elegans</i>

2021-04-16

Abstract excerpt

When exposed to stressful conditions, eukaryotic cells respond by inducing the formation of cytoplasmic ribonucleoprotein complexes called stress granules. Stress granules are thought to have a protective function but their exact role is still unclear. Here we use C. elegans to study two proteins that have been shown to be important for stress granule assembly in human cells: PQN-59, the ortholog of human UBAP2L,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6519384-e920-5e7b-a7ca-3d5c9d4aa594
DOI: 10.1101/2021.04.16.440123

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The UBAP2L ortholog PQN-59 contributes to stress granule assembly and development in <i>C. elegans</i>DOI 10.1101/2021.04.16.440123Read

Heat stress-induced condensation of G3BP1 in perinuclear P-bodies in <i>C. elegans’</i> germlineSemantic proximity Read

P Granule Assembly and Function in <i>Caenorhabditis elegans</i> Germ CellsSemantic proximity Read

PQN-59 antagonizes microRNA-mediated repression and functions in stress granule formation during <i>C. elegans</i> developmentSemantic proximity Read

Compartmentalized localization of perinuclear proteins within germ granules in <i>C. elegans</i>Semantic proximity Read

Connecting the Dots: Linking Caenorhabditis elegans Small RNA Pathways and Germ Granules.Semantic proximity Read

The diverse functions of germline P‐granules in Caenorhabditis elegansSemantic proximity Read

PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.Semantic proximity Read

Arabidopsis thaliana G3BP Ortholog Rescues Mammalian Stress Granule Phenotype across Kingdoms.Semantic proximity Read

Germ granules prevent accumulation of somatic transcripts in the adult <i>C. elegans</i> germlineSemantic proximity Read

TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in <i>C. elegans</i>Semantic proximity Read

P granules protect RNA interference genes from silencing by piRNAsSemantic proximity Read

eIF4E assembly into <i>C. elegans</i> germ granules is essential for its repressive functionSemantic proximity Read