Article

Cancer-associated fibroblasts induced by colorectal cancer cells inhibit γδT cells killing function through the ERK/COX-2/PGE2 pathways

2024-01-19

Abstract excerpt

The tumor microenvironment (TME) is a highly ordered ecosystem in which several non-malignant cell types, including immune cells, cancer-associated fibroblasts (CAFs), and other cell types, are encircled by cancer cells. Colorectal cancer (CRC) is determined by the reciprocal contact between cancer cells and host cells. γδT cells represent a significant subset of the natural immune system and are vital in the batt...

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Literature Corpus work: d6369a52-2a7b-5f70-b1bd-8012e201834c
DOI: 10.21203/rs.3.rs-3874261/v1

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