Article

Further Evidence of Early-Onset Osteoporosis and Bone Fractures as a New <i>FGFR2</i>-Related Phenotype

2025-03-05

Abstract excerpt

<h4>Background: </h4> primary osteoporosis in children and young adults often suggests a monogenic disease affecting bone microarchitecture and bone mineral density. While Osteogenesis Imperfecta (OI) is the most recognized genetic cause of recurrent fractures, many other genes involved in bone metabolism may contribute to osteoporosis. Among them, FGFR2 plays a critical role in bone growth and development by regu...

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Literature Corpus work: d630a7f9-bf36-518e-9c6d-1af6123b4142
DOI: 10.20944/preprints202503.0306.v1

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