Article

Prevalence of antibodies against adeno-associated viruses (AAVs) in Göttingen Minipigs: Implications for Gene Therapy and Xenotransplantation

2024-03-25

Abstract excerpt

<title>Abstract</title> <p>Adenovirus associated viruses (AAV) are well established in clinical trials for in vivo gene therapy. The AAV vector has unique features that are beneficial in clinical applications including broad tropism, low immunogenicity, ease of production, it is non-pathogenic, rarely integrates into the host chromosome and results in long-term expression of the transgene. Göttingen Minipigs are...

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Literature Corpus work: d62293c2-b838-5063-b0a7-d875fe48ac4b
DOI: 10.21203/rs.3.rs-3981828/v1

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