Article
Genetics of Atrial Fibrillation: State of the Art in 2017.
Heart, lung & circulation - 1 Sept 2017
Fatkin Diane, Santiago Celine F, Huttner Inken G, Lubitz Steven A, Ellinor Patrick T
Abstract excerpt
Genetic variation is an important determinant of atrial fibrillation (AF) susceptibility. Numerous rare variants in protein-coding sequences of genes have been associated with AF in families and in early-onset cases, and chromosomal loci harbouring common risk variants have been mapped in AF cohorts. Many of these loci are in non-coding regions of the human genome and are thought to contain regulatory sequences...
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