Article

Genomic analyses identify key biological processes in prototype foamy virus infected cancer cells

2022-05-02

Abstract excerpt

Viral vector-mediated gene therapy against cancer such as fibrosarcoma has been considered a high gene delivery method. Among the retroviruses, foamy viruses have been considered potential gene therapy vectors due to their non-pathogenicity. However, the biological processes during the foamy viruses infected cancer cells are unknown. Here, our objective is to figure out the key molecules, signaling pathways, and b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5e6c790-1242-5e1c-929c-b87c883c7fbb
DOI: 10.21203/rs.3.rs-1617170/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomic analyses identify key biological processes in prototype foamy virus infected cancer cellsDOI 10.21203/rs.3.rs-1617170/v1Read

Global Lipidomic Analysis of Lytic KSHV Infection: The lipid chaperone FABP4 is required for maximal infectious virion productionSemantic proximity Read

Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolismSemantic proximity Read

Single cell analysis revealed SFRP2 cancer associated fibroblasts drive tumorigenesis in head and neck squamous cell carcinomaSemantic proximity Read

A defective human foamy provirus generated by pregenome splicing.Semantic proximity Read

Oncogenic Mechanisms of Kaposi's Sarcoma‐Associated Herpesvirus on Cell Metabolism and Cell TransformationSemantic proximity Read

Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression.Semantic proximity Read

Rewiring of the host cell metabolome and lipidome during lytic gammaherpesvirus infection is essential for infectious virus productionSemantic proximity Read

KSHV Reprograms Host RNA Splicing via FAM50A to Activate STAT3 and Drive Oncogenic Cellular TransformationSemantic proximity Read

RNA-Seq of Kaposi’s sarcoma reveals alterations in glucose and lipid metabolismSemantic proximity Read

Single-cell RNA sequencing identifies KSHV-infected Mesenchymal stem cell subpopulations precursors of Kaposi’s SarcomaSemantic proximity Read

From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolismSemantic proximity Read

Targeting Host Cellular Factors as a Strategy of Therapeutic Intervention for Herpesvirus InfectionsSemantic proximity Read