Article

Methylation Data Processing Protocol & Comparison of Blood and Cerebral Spinal Fluid Following Aneurysmal Subarachnoid Hemorrhage

2020-03-25

Abstract excerpt

One challenge in conducting DNA methylation-based epigenome-wide association studies (EWAS) is the appropriate cleaning and quality-checking of the methylation values to minimize biases and experimental artifacts, while simultaneously retaining potential biological signals. These issues are compounded in studies that include multiple tissue types, and/or tissues for which reference data are unavailable to assist i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5c8d5f7-f770-5084-9142-7e4d786c42b7
DOI: 10.1101/2020.03.24.005264

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Methylation Data Processing Protocol & Comparison of Blood and Cerebral Spinal Fluid Following Aneurysmal Subarachnoid HemorrhageDOI 10.1101/2020.03.24.005264Read

The Role of Epigenetics in Brain Aneurysm and Subarachnoid Hemorrhage: A Comprehensive ReviewSemantic proximity Read

Genome-Wide DNA Methylation Pattern in Whole Blood Associated With Primary Intracerebral HemorrhageSemantic proximity Read

Genome-wide blood DNA methylation analysis in patients with delayed cerebral ischemia after subarachnoid hemorrhageSemantic proximity Read

Non‐invasive epigenomic molecular phenotyping of the human brain via liquid biopsy of cerebrospinal fluid and next generation sequencingSemantic proximity Read

m6A regulator–mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in patients with intracranial aneurysmsSemantic proximity Read

Genome-wide DNA methylation analysis of post-operative delirium with brain, blood, saliva, and buccal samples from neurosurgery patientsSemantic proximity Read

Iron homeostasis pathway DNA methylation trajectories reveal a role for STEAP3 metalloreductase in patient outcomes after aneurysmal subarachnoid hemorrhageSemantic proximity Read

Peripheral blood DNA methylation partially reports on immune cell type composition in the frontal brainSemantic proximity Read

Genome-Wide DNA Methylation Profiling Reveals Low Methylation Variability in Moyamoya DiseaseSemantic proximity Read

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium.Semantic proximity Read

DNA methylation and stroke prognosis: an epigenome-wide association studySemantic proximity Read

DNA Methylation-estimated Phenotypes, Telomere length, Aging and Risk of Intracranial Aneurysms: Evidence from genetic studiesSemantic proximity Read