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Genome-Wide DNA Methylation Profiling Reveals Low Methylation Variability in Moyamoya Disease

2 Oct 2024

Abstract excerpt

Moyamoya disease (MMD) is a chronic cerebrovascular disorder that can lead to stroke and neurological dysfunctions. Given the largely sporadic nature and the role of gene-environment interactions in various diseases, we examined epigenetic modifications in MMD. We performed genome-wide DNA methylation using Illumina 850 K Methylation EPIC BeadChip, in two racially distinct adult female cohorts: a non-Asian cohort...

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PMID: 39356405
DOI: 10.1007/s12975-024-01299-w

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