Article

Longitudinal Gut Microbiota Tracking Reveals the Persistent Spread of Mobile Genes and HGT-Driven Community Stabilization

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>Horizontal gene transfer (HGT) is a major driver of bacterial evolution, but its role in shaping the human gut microbiome over time remains poorly understood. Here, we present a longitudinal metagenomic analysis of 676 fecal samples from 338 individuals collected ~4 years apart, using a newly developed workflow to detect recent HGT events from metagenome-assembled genomes. We identified...

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Literature Corpus work: d5583c2e-e11d-58db-a2de-159fe2b390e6
DOI: 10.21203/rs.3.rs-6509357/v1

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