Article

Comprehensive analysis of mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene pools

2017-11-06

Abstract excerpt

Mobile genetic elements (MGEs) drive extensive horizontal transfer in the gut microbiome. This transfer could benefit human health by conferring new metabolic capabilities to commensal microbes, or it could threaten human health by spreading antibiotic resistance genes to pathogens. Despite their biological importance and medical relevance, MGEs from the gut microbiome have not been systematically characterized. H...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78c5d670-8158-5d03-a075-b88358edb256
DOI: 10.1101/214213

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive analysis of mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene poolsDOI 10.1101/214213Read

Comprehensive analysis of chromosomal mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene poolsSemantic proximity Read

Interrogation of the integrated mobile genetic elements in gut-associated <i>Bacteroidaceae</i> with a consensus prediction approachSemantic proximity Read

Mobile genetic element insertions drive antibiotic resistance across pathogensSemantic proximity Read

The ESKAPE mobilome contributes to the spread of antimicrobial resistance and CRISPR-mediated conflict between mobile genetic elementsSemantic proximity Read

Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-CSemantic proximity Read

A Novel and Direct Metamobilome Approach improves the Detection of Larger-sized Circular Elements across KingdomsSemantic proximity Read

Mobile genetic elements of the human gastrointestinal tractSemantic proximity Read

Investigation of mobile genetic elements and their association with antibiotic resistance genes in clinical pathogens worldwideSemantic proximity Read

In vitro demonstration of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiomeSemantic proximity Read

Single Amplified Genome Catalog Reveals the Dynamics of Mobilome and Resistome in the Human MicrobiomeSemantic proximity Read

A metagenomics pipeline reveals insertion sequence-driven evolution of the microbiotaSemantic proximity Read

Mobile Type VI secretion system loci of the gut Bacteroidales display extensive intra-ecosystem transfer, multi-species spread and geographical clusteringSemantic proximity Read