Article

A centrosome calcium signal is essential for mammalian cell mitosis

2018-07-30

Abstract excerpt

To generate a complex multicellular organism like a human requires enormous expansion in cell numbers and this is achieved predominantly through mitosis. Defects in mitosis can lead to premature ageing and cancer so understanding how it is regulated has important implications for human disease. Early data from plant and invertebrate model systems indicated that calcium (Ca 2+ ) could influence mitosis. Here we ex...

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Literature Corpus work: d53ea1a4-3b36-56e7-9249-a5e46d6e382b
DOI: 10.1101/379792

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