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Urinary cell mRNA profiling of kidney allograft recipients: Development of a portable protocol for noninvasive diagnosis of T cell mediated rejection and BK virus nephropathy

2022-09-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> We developed urinary cell mRNA profiling for the noninvasive diagnosis of acute T cell mediated rejection (TCMR) and BK virus nephropathy (BKVN), two significant post-transplant complications. Our profiling protocol for the multicenter Clinical Trial of Transplantation-04 (CTOT-04) study consisted of centrifugation of urine to prepare cell pellets, washes, addition of an RNA p...

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Literature Corpus work
d539ad74-fef7-54e2-bfb8-9c1b1c90e6f3
DOI
10.1101/2022.09.15.22279980
Open publication

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Urinary cell mRNA profiling of kidney allograft recipients: Development of a portable protocol for noninvasive diagnosis of T cell mediated rejection and BK virus nephropathyDOI 10.1101/2022.09.15.22279980
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