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Article

YTHDF1 promotes intrahepatic cholangiocarcinoma progression via regulating EGFR mRNA translation

2 Mar 2022

Abstract excerpt

Abstract Background and Aim Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive disease with the underlying mechanisms poorly understood. YTHDF1, an N6‐methyladenosine (m6A) reader protein, has important physiological functions in regulation of tumor development. However, the effect of YTHDF1 on ICC progression remains unknown yet. Methods The expression level of YTHDF1 in human ICC tissue was examined...

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PMID: 35233828
DOI: 10.1111/jgh.15816

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