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Combinatorial phenotypic landscape enables bacterial resistance to phage infection

2025-01-15

Abstract excerpt

<h4> Abstract </h4> Success of phage therapies is limited by bacterial defenses against phages. While a large variety of anti- phage defense mechanisms has been characterized, how expression of these systems is distributed across individual cells and how their combined activities translate into protection from phages has not been studied. Using bacterial single-cell RNA sequencing, we profiled the transcriptomes...

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Literature Corpus work
d525d6a7-1a29-5713-a0f6-46662e2c6acb
DOI
10.1101/2025.01.13.632860
Open publication

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Combinatorial phenotypic landscape enables bacterial resistance to phage infectionDOI 10.1101/2025.01.13.632860
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