Article
High-throughput mapping of the phage resistance landscape in E. coli.
PLoS biology - 1 Oct 2020
Mutalik Vivek K, Adler Benjamin A, Rishi Harneet S, Piya Denish, Zhong Crystal, Koskella Britt, Kutter Elizabeth M, Calendar Richard, Novichkov Pavel S, Price Morgan N, Deutschbauer Adam M, Arkin Adam P
Abstract excerpt
Bacteriophages (phages) are critical players in the dynamics and function of microbial communities and drive processes as diverse as global biogeochemical cycles and human health. Phages tend to be predators finely tuned to attack specific hosts, even down to the strain level, which in turn defend themselves using an array of mechanisms. However, to date, efforts to rapidly and comprehensively identify bacterial...
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