Article

Automated Prediction of Fibroblast Phenotypes Using Mathematical Descriptors of Cellular Features

2024-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Fibrosis is caused by pathological activation of resident fibroblasts to myofibroblasts that leads to aberrant tissue stiffening and diminished function of affected organs with limited pharmacological interventions. Despite the prevalence of myofibroblasts in fibrotic tissue, existing methods to grade fibroblast phenotypes are typically subjective and qualitative, yet important for screening of...

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Literature Corpus work: 965e46df-46dd-5193-a465-3c6ffd0c4ba4
DOI: 10.1101/2024.05.15.594418

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