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A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.

2024-04-18

Abstract excerpt

<title>Abstract</title> <p>Transcribed Ultra-Conserved Regions (TUCRs) represent a severely understudied class of putative non-coding RNAs (ncRNAs) that are 100% conserved across multiple species. We performed the first-ever analysis of TUCRs in glioblastoma (GBM) and low-grade gliomas (LGG). We leveraged large human datasets to identify the genomic locations, chromatin accessibility, transcription, differential...

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Literature Corpus work
d4bb5112-2ead-54de-aa5f-f315723de5f2
DOI
10.21203/rs.3.rs-4164642/v1
Open publication

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