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Article

The dark matter of the human genome and its role in human cancers.

Gene - 15 Feb 2022

Bozgeyik Ibrahim

Abstract excerpt

The transcribed ultra-conserved regions (T-UCRs) are a novel family of non-coding RNAs which are absolutely conserved (100%) across orthologous regions of the human, mouse, and rat genomes. T-UCRs represent a small portion of the human genome that is likely to be functional but does not code for proteins and is referred to as the "dark matter" of the human genome. Although T-UCRs are ubiquitously expressed,...

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Identifiers

PMID: 34843880
DOI: 10.1016/j.gene.2021.146084

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