Article

Preclinical <i>CRX</i> augmentation therapies for <i>CRX</i> -associated autosomal dominant cone-rod dystrophies

2026-02-24

Abstract excerpt

<h4>ABSTRACT</h4> Cone-rod dystrophies (CoRD) are inherited retinal diseases (IRDs) with variable ages of onset, characterized by the progressive loss of cones, followed by secondary degeneration of rods. Cone-rod homeobox (CRX) is a transcription factor that regulates gene expression essential for photoreceptor development and maintenance. Mutations in CRX gene, including CRX E168d2 and CRX E80A , are impli...

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Literature Corpus work: d4a294c3-ac85-521c-ae03-ea1aa5004911
DOI: 10.64898/2026.02.23.707517

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