Article

Whole Exon Sequencing of Primary Lesion and Liver Metastatic Lesion in Pancreatic Neuroendocrine Tumor：A Case Report and Review of the Literature

2021-09-07

Abstract excerpt

<h4>Background: </h4> Pancreatic neuroendocrine neoplasms(p-NENs) are classified into neuroendocrine tumors (NET) G1, G2, G3, and neuroendocrine carcinoma (NEC) according to WHO classification. NET and NEC are different pathogenesis. The two kinds of tumors that occurred in the same part have not been reported. We found 4 foci of NEN G3 in a primary pancreatic NET G2. The cell atypia was obvious with Ki67 index of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d49164ad-c6a2-50ee-b191-64f37a95eeb8
DOI: 10.21203/rs.3.rs-796608/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole Exon Sequencing of Primary Lesion and Liver Metastatic Lesion in Pancreatic Neuroendocrine Tumor：A Case Report and Review of the LiteratureDOI 10.21203/rs.3.rs-796608/v1Read

Molecular Classification of Gastrointestinal and Pancreatic Neuroendocrine Neoplasms: Are We Ready for That?Semantic proximity Read

Pancreatic Neuroendocrine Neoplasms: Basic Biology, Current Treatment Strategies and Prospects for the FutureSemantic proximity Read

Targeted deep sequencing reveals the genetic heterogeneity in well-differentiated pancreatic neuroendocrine tumors with liver metastasisSemantic proximity Read

Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological gradingSemantic proximity Read

Molecular Basis of Pancreatic Neuroendocrine TumorsSemantic proximity Read

Molecular and Functional Heterogeneity of Primary Pancreatic Neuroendocrine Tumors and Metastases.Semantic proximity Read

Pancreatic neuroendocrine neoplasms: Updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classificationSemantic proximity Read

Targeted-Gene Sequencing and Bioinformatics Analysis of Patients with Gallbladder Neuroendocrine Carcinoma: A Case Report and Literature ReviewSemantic proximity Read

Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.Semantic proximity Read

Genetic alterations of GI-NECs involving three main signaling pathways.Semantic proximity Read

Application of multiomics sequencing and advances in the molecular mechanisms of pancreatic neuroendocrine neoplasms.Semantic proximity Read

Tumor mutation burden in gastro-entero-pancreatic-neuroendocrine neoplasmsSemantic proximity Read