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Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based Study

2025-05-08

Abstract excerpt

This study addresses the issue of whether orally administered zinc (gluconate) (26 mg BID) can induce remodeling of gastrointestinal barrier function and reduce passive leak across the human intestinal mucosal barrier in situ. It represents the first patient-based study to examine the effect of zinc on GI epithelial tight junctions and GI barrier leak in otherwise healthy test subjects. Using independent test subj...

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Literature Corpus work: d439fffb-821d-526f-9e88-323da06253f2
DOI: 10.20944/preprints202505.0528.v1

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Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based StudyDOI 10.20944/preprints202505.0528.v1Read

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