Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice

26 Mar 2024

Abstract excerpt

Host molecular responses to fecal microbiota transplantation (FMT) in ulcerative colitis are not well understood. Here, we profile the human colonic mucosal transcriptome prior to and following FMT or placebo to identify molecules regulated during disease remission. FMT alters the transcriptome above the effect of placebo (n = 75 vs 3 genes, q < 0.05), including modulation of structural, metabolic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Microscopic Colitis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38531874
DOI: 10.1038/s41467-024-46983-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and micePMID 38531874Read ↗

Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut.Semantic proximity Read ↗

Large-scale transcriptomic meta-analysis identifies novel therapeutic targets for ulcerative colitisSemantic proximity Read ↗

Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis.Semantic proximity Read ↗

The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencingSemantic proximity Read ↗

Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel DiseasesSemantic proximity Read ↗

Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiomeSemantic proximity Read ↗

Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel diseaseSemantic proximity Read ↗

Identification and immunoinfiltration analysis of key genes in ulcerative colitis using WGCNASemantic proximity Read ↗

Unveiling the Porphyromonadaceae- <i>TFF1</i> Interaction and <i>ITGAM</i> as Critical Factors in Post-operative Recurrence of Crohn’s DiseaseSemantic proximity Read ↗

RhoB affects colitis through modulating cell signaling and intestinal microbiomeSemantic proximity Read ↗

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitisSemantic proximity Read ↗

Gut Microbiota Dysbiosis Drives Myocardial Hypertrophy Through GBP2b/GBP1-Mediated Immune Reprogramming and Exosomal Signaling in Chronic ColitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.