Article

Maternal gestational diabetes mellitus modulates adipose tissue remodeling and CTRP6 expression in a depot- and sex-specific manner in mouse offspring

2025-11-21

Abstract excerpt

<title>Abstract</title> <p>Objective This study aimed to explore how maternal gestational diabetes mellitus (GDM) affects adipose tissue remodeling and the expression of C1q/TNF-related protein 6 (CTRP6) in offspring, with a focus on sex- and depot-specific differences. Methods A GDM mouse model was established by feeding female C57BL/6J mice a high-fat diet (HFD) before and during pregnancy. Offspring were weane...

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Literature Corpus work: d3fcf002-5466-5e7c-9027-1ca2bf07afe7
DOI: 10.21203/rs.3.rs-8114097/v1

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