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The SARS-CoV-2 Y453F mink variant displays a striking increase in ACE-2 affinity but does not challenge antibody neutralization

2021-01-29

Abstract excerpt

SARS-CoV-2 transmission from humans to animals has been reported for many domesticated species, including cats, dogs and minks. Identification of novel spike gene mutations appearing in minks has raised major concerns about potential immune evasion and challenges for the global vaccine strategy. The genetic variant, known as “cluster-five”, arose among farmed minks in Denmark and resulted in a complete shutdown of...

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Literature Corpus work
d3c1917c-e538-5a80-a2de-922d42682d7b
DOI
10.1101/2021.01.29.428834
Open publication

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The SARS-CoV-2 Y453F mink variant displays a striking increase in ACE-2 affinity but does not challenge antibody neutralizationDOI 10.1101/2021.01.29.428834
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