Article

Broadly neutralizing antibodies target the coronavirus fusion peptide

2022-04-12

Abstract excerpt

The potential for future coronavirus outbreaks highlights the need to develop strategies and tools to broadly target this group of pathogens. Here, using an epitope-agnostic approach, we identified six monoclonal antibodies that bound to spike proteins from all seven human-infecting coronaviruses. Epitope mapping revealed that all six antibodies target the conserved fusion peptide region adjacent to the S2’ cleava...

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Literature Corpus work: d3aa3b50-cad0-5265-978e-ca40a1235493
DOI: 10.1101/2022.04.11.487879

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