Article
Co-regulatory Network of RNA-Binding Proteins and Alternative Splicing in the Pathogenesis of Lupus Nephritis
2025-08-22
Abstract excerpt
<title>Abstract</title> <p>Lupus nephritis (LN), the most severe complication of systemic lupus erythematosus (SLE), remains incompletely understood at the molecular level. This study systematically investigates the regulatory roles and immune relevance of RNA-binding proteins (RBPs) and alternative splicing (AS) in LN through integrated bioinformatics analysis and experimental validation. Utilizing RNA sequencin...
Topics
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- Atherosclerosis and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Protein Tyrosine Phosphatases
- Renal Diseases and Glomerulopathies
- Single-cell and spatial transcriptomics
- Systemic Lupus Erythematosus Research
Identifiers and source
- Literature Corpus work
- d364bfa6-2569-5594-b527-0901e4bc6418
- DOI
- 10.21203/rs.3.rs-7090892/v1
