Remodelling Ca2+ signalling systems and cardiac hypertrophy

Abstract excerpt

In cardiac cells, Ca2+ signals appear as brief transients responsible for controlling both contraction and transcription. Information may be encoded in these digital signals through changes in both frequency and shape. An increase in Ca2+ signalling contributes to a process of phenotypic remodelling during hypertrophy. The increase in Ca2+ that drives the larger contractions may be responsible for switching on a s...

Topics

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• Cardiac electrophysiology and arrhythmias
• Ion Channels and Receptors
• Signaling Pathways in Disease

Identifiers and source

Literature Corpus work

d305d457-2e69-5216-8ab6-df9b91131fa5

DOI

10.1042/bst0340228