Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcium and cardiomyopathies.

Sub-cellular biochemistry - 1 Jan 2007

Kranias E G, Bers D M

Abstract excerpt

Regulation of Calcium (Ca) cycling by the sarcoplasmic reticulum (SR) underlies the control of cardiac contraction during excitation-contraction (E-C) coupling. Moreover, alterations in E-C coupling occurring in cardiac hypertrophy and heart failure are characterized by abnormal Ca-cycling through the SR network. A large body of evidence points to the central role of: a) SERCA and its regulator phospholamban...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Receptors, Adrenergic, beta
Share to Ryanodine Receptor Calcium Release Channel
Share to Sarcoplasmic Reticulum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sarcoplasmic Reticulum Calcium-Transporting ATPases

Share to Calcium-Calmodulin-Dependent Protein Kinases

Share to Calcium Signaling

Share to Calsequestrin

Share to Heart Failure

Source

Identifiers

PMID: 18193651
DOI: 10.1007/978-1-4020-6191-2_20

Genes

PLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcium and cardiomyopathies.PMID 18193651Read ↗

Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia.Semantic proximity Read ↗

Sarcoplasmic reticulum Ca-ATPase-phospholamban interactions and dilated cardiomyopathy.Semantic proximity Read ↗

Sarcoplasmic Reticulum Ca2+ Dysregulation in the Pathophysiology of Inherited Arrhythmia: An Update.Semantic proximity Read ↗

Myocardial calcium signalling and arrhythmia pathogenesis.Semantic proximity Read ↗

Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias.Semantic proximity Read ↗

Beyond the cardiac myofilament: hypertrophic cardiomyopathy- associated mutations in genes that encode calcium-handling proteins.Semantic proximity Read ↗

Dysfunction of Ca2+ Channels in Hereditary and Chronic Cardiovascular DiseasesSemantic proximity Read ↗

Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target.Semantic proximity Read ↗

Arrhythmia-associated cardiac Ca²(+) cycling proteins and gene mutations.Semantic proximity Read ↗

Ca2+ signalling and muscle disease.Semantic proximity Read ↗

A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia.Semantic proximity Read ↗

Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.