Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells

13 Aug 2015

Abstract excerpt

To meet the need of a large quantity of hPSC-derived cardiomyocytes (CM) for pre-clinical and clinical studies, a robust and scalable differentiation system for CM production is essential. With a human pluripotent stem cells (hPSC) aggregate suspension culture system we established previously, we developed a matrix-free, scalable, and GMP-compliant process for directing hPSC differentiation to CM in suspension...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26318718
DOI: 10.1016/j.scr.2015.08.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cellsPMID 26318718Read ↗

A Universal and Robust Integrated Platform for the Scalable Production of Human Cardiomyocytes From Pluripotent Stem CellsSemantic proximity Read ↗

Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactorSemantic proximity Read ↗

Bioreactor Suspension Culture: Differentiation and Production of Cardiomyocyte Spheroids From Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Controlling Expansion and Cardiomyogenic Differentiation of Human Pluripotent Stem Cells in Scalable Suspension CultureSemantic proximity Read ↗

Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservationSemantic proximity Read ↗

Considerations in designing systems for large scale production of human cardiomyocytes from pluripotent stem cellsSemantic proximity Read ↗

Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiationSemantic proximity Read ↗

Suspension culture on microcarriers and as aggregates enables expansion and differentiation of pluripotent stem cells (PSCs)Semantic proximity Read ↗

Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiationSemantic proximity Read ↗

Simple suspension culture system of human iPS cells maintaining their pluripotency for cardiac cell sheet engineeringSemantic proximity Read ↗

Growth Factor-Based Manufacturing of Human Pluripotent Stem Cell-Derived Cardiomyocytes Using the Vertical Wheel Bioreactor SystemSemantic proximity Read ↗

Current Strategies and Challenges for Purification of Cardiomyocytes Derived from Human Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.