Article

Widespread dysregulation of long non-coding genes associated with fatty acid metabolism, cell division, and immune response gene networks in xenobiotic-exposed rat liver

2019-10-03

Abstract excerpt

Xenobiotic exposure activates or inhibits transcription of hundreds of protein-coding genes in mammalian liver, impacting many physiological processes and inducing diverse toxicological responses. Little is known about the effects of xenobiotic exposure on long noncoding RNAs (lncRNAs), many of which play critical roles in regulating gene expression. <h4>Objective:</h4> to develop a computational framework to disc...

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Literature Corpus work: d1f9d006-6ddb-5939-855b-1d034325f086
DOI: 10.1101/791772

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