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Article

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre-cancer lesions

2025-07-30

Abstract excerpt

Patients with lung squamous cell carcinoma (LUSC) are often diagnosed at advanced stages, limiting opportunities for early intervention. LUSC develops through a multistep progression from low-grade lesions to high-grade lesions, including carcinoma in situ (CIS), of which approximately half progress to invasive cancer while the other half regress. Although frequent mutations and copy number alterations have been d...

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Literature Corpus work
d1e54ffd-8d1e-54c2-bc70-b5c6837db555
DOI
10.1101/2025.07.29.664792
Open publication

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Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre-cancer lesionsDOI 10.1101/2025.07.29.664792
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