Article

Increased cell size, structural complexity and migration of cancer cells acquiring fibroblast organelles by cell-projection pumping

2019-09-16

Abstract excerpt

We recently described a hydrodynamic mechanism for cytoplasmic transfer between cells, termed cell-projection pumping (CPP). Earlier image analysis related altered SAOS-2 osteosarcoma cell morphology, to what we now recognize as CPP uptake of fibroblast cytoplasm. We here examine SAOS-2 phenotype following co-culture with human dermal fibroblasts (HDF) in which organelles were pre-labelled with a fluorescent lipop...

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Literature Corpus work: d1a36be7-ca75-5afe-a2f0-844b4e0bce11
DOI: 10.1101/770693

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