Article

Bacterial community modifies host genetics effect on early childhood caries

2023-01-11

Abstract excerpt

<h4>Background</h4> By age five approximately one-fifth of children have early childhood caries (ECC). Both the oral microbiome and host genetics are thought to influence susceptibility. Whether the oral microbiome modifies genetic susceptibility to ECC has not been tested. We test whether the salivary bacteriome modifies the association of a polygenic score (PGS, a score derived from genomic data that summarizes...

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Literature Corpus work: d16afe7b-faa6-5864-a469-16d658b0bb0a
DOI: 10.1101/2023.01.11.23284235

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