Bacterial Community Modifies Host Genetics Effect on Early Childhood Caries.

doi:10.1177/00220345231175356

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Bacterial Community Modifies Host Genetics Effect on Early Childhood Caries.

Journal of dental research - 1 Sept 2023

Blostein F, Zou T, Bhaumik D, Salzman E, Bakulski K M, Shaffer J R, Marazita M L, Foxman B

Abstract excerpt

By age 5, approximately one-fifth of children have early childhood caries (ECC). Both the oral microbiome and host genetics are thought to influence susceptibility. Whether the oral microbiome modifies genetic susceptibility to ECC has not been tested. We test whether the salivary bacteriome modifies the association of a polygenic score (PGS, a score derived from genomic data that summarizes genetic...

Topics

Child, Preschool
Humans
Bacteria
Dental Caries
Dental Caries Susceptibility
Genetic Predisposition to Disease
Genome-Wide Association Study
Saliva
Meta-Analysis as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 37395259
DOI: 10.1177/00220345231175356
PMCID: PMC10552462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics