Article
Strain-level genomic variation of Streptococcus mutans and early childhood caries in preschool children from Northern Arizona and Hawaii.
PeerJ - 1 Jan 2026
Whealy Ryann N, Furstenau Tara N, Roberts Alex, Cocking Jill Hager, Erickson Daryn, Brock Breezy, McCormick Rowan, Timm Skylar, Pacheco Misty, Mochida-Meek Summer, Fofanov Viacheslav
Abstract excerpt
Background: Early childhood caries (ECC) is the most common chronic disease of childhood, with especially high prevalence in Arizona and Hawaii where several racial and ethnic groups experience disproportionate burden. Although ECC is a polymicrobial disease, Streptococcus mutans plays a central role in its development, and evidence suggests that strain-level genetic variation influences its cariogenic potential....
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