Back to search

Article

Antitumor Effects of Cannabidiol (CBD) on Osteosarcoma by Targeting TNF-α/NF-κB/CCL5 Signaling Axis

2025-02-19

Abstract excerpt

<h4>Background: </h4> and Purpose: Osteosarcoma presents significant clinical challenges due to its aggressive nature and propensity for metastasis, prompting the investigation of alternative treatment strategies. CBD has demonstrated potential in cancer treatment. This study aims to elucidate the effect of CBD on the malignant phenotype of osteosarcoma and to investigate its molecular mechanisms. Experimental App...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d087e489-2645-58e4-a83c-29b2057b276d
DOI
10.22541/au.173995580.00992363/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Antitumor Effects of Cannabidiol (CBD) on Osteosarcoma by Targeting TNF-α/NF-κB/CCL5 Signaling AxisDOI 10.22541/au.173995580.00992363/v1
Cannabidiol reverts the malignant phenotype of hepatocellular carcinoma cells via the GPR55/TP53/MAPK axis.Semantic proximity
The strengths and limits of cannabinoids and their receptors in cancer: Insights into the role of tumorigenesis-underlying mechanisms and therapeutic aspectsSemantic proximity
Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection against osteosarcomaSemantic proximity
Network pharmacology, bioinformatics, molecular docking and experimental verification of the mechanism of HXZTS treatment on osteoarthritis synoviumSemantic proximity
The mechanism of CPT1A involved in hepatocellular carcinoma growth and Bufalin regulates malignant behavior of hepatocellular carcinoma via CPT1ASemantic proximity
Exploration in the Mechanism of Ginsenoside Rg5 for the Treatment of Osteosarcoma by Network Pharmacology and Molecular DockingSemantic proximity
Oleanolic Acid Inhibits the Proliferation and Invasion of U251Glioma Cells and Promotes their Apoptosis through the IKK-β, MAPK3, and MAPK4 Signaling PathwaySemantic proximity
Comparative transcriptomics and network pharmacology analysis to identify the potential mechanism of celastrol against osteoarthritisSemantic proximity
A Network Pharmacology Approach to Identify Potential Molecular Targets for Cannabidiol's Anti-Inflammatory ActivitySemantic proximity
Anti-tumor effects of cryptotanshinone (C19H20O3) in human osteosarcoma cell linesSemantic proximity
Bufalin-Mediated Regulation of Cell Signaling Pathways in Different Cancers: Spotlight on JAK/STAT, Wnt/β-Catenin, mTOR, TRAIL/TRAIL-R, and Non-Coding RNAsSemantic proximity
Exploring the Efficacy of a Novel Cannabidiol and Bevacizumab Combination in Non-Small Cell Lung CancerSemantic proximity
Select a neighboring publication to make it the new centre.