Article

Plasmid dispersal and recombination across human gut microbiomes is neutral, but overpowered by inflammatory diseases

2023-09-15

Abstract excerpt

<title>Abstract</title> <p>Plasmids are pivotal in driving bacterial evolution through horizontal gene transfer. Here, we investigated 3,467 human gut microbiome samples across continents and disease states, analyzing 11,086 plasmids. Our analyses reveal that plasmid dispersal is predominantly stochastic, indicating neutral processes as the primary driver of their wide distribution. We find that only 20-25% of pl...

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Literature Corpus work: d04d8ae7-a9de-59d1-9c91-653b90a1394a
DOI: 10.21203/rs.3.rs-3272455/v1

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