Article

Association between creatinine-to-cystatin C ratio and ALSFRS-R across clinical phenotypes

2026-03-20

Abstract excerpt

<title>Abstract</title> <p> Background Reliable and accessible biomarkers for amyotrophic lateral sclerosis (ALS) are scarce. Creatinine (Cre) reflects muscle mass, whereas cystatin C (CysC) reflects neurodegeneration without affecting muscle mass; however, both have limitations. We aimed to investigate whether the creatinine-to-cystatin C ratio (Cre/CysC) could serve as a robust indicator of functional status...

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Literature Corpus work: d000ff2c-7593-5979-b5ca-eb076fcbe337
DOI: 10.21203/rs.3.rs-8953813/v1

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