Back to search

Article

An inflammatory gene set–driven epigenetic clock tracks down disease progression and rejuvenation

2026-06-06

Abstract excerpt

Chronic, low-level inflammation, characterized by elevated pro-inflammatory programs, including epigenetic changes, in the absence of infection, is a major driver of aging and age-related diseases. On the other side of the spectrum, aging interventions work, at least in part, by decreasing inflammation. However, the molecular connection between epigenetic aging and inflammatory profiles in chronic diseases and rej...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cfc0e190-a85e-5806-9776-1ffafba143e1
DOI
10.64898/2026.06.04.730043
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An inflammatory gene set–driven epigenetic clock tracks down disease progression and rejuvenationDOI 10.64898/2026.06.04.730043
EpInflammAge: Epigenetic-Inflammatory Clock for Disease-Associated Biological Aging Based on Deep LearningSemantic proximity
Systemic inflammation and biological aging in the Health and Retirement StudySemantic proximity
Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohortsSemantic proximity
Molecular and genetic inflammation networks in major human diseases.Semantic proximity
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular agingSemantic proximity
An epigenetic biomarker of aging for lifespan and healthspanSemantic proximity
An Inflammatory and Quiescent HSC Subpopulation Expands with Age in HumansSemantic proximity
An epigenetic biomarker of aging for lifespan and healthspanSemantic proximity
EpImAge: An Epigenetic-Immune Clock for Disease-Associated Biological AgingSemantic proximity
Various diseases and conditions are strongly associated with the next-generation epigenetic aging clock CheekAgeSemantic proximity
Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammagingSemantic proximity
Critical review of aging clocks and factors that may influence the pace of agingSemantic proximity
Select a neighboring publication to make it the new centre.