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CDH26 amplifies airway epithelial IL-4 receptor α signaling in asthma

2020-12-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Activation of interleukin (IL)-4 receptor (R) signaling in airway epithelial cells leads to airway hyperresponsiveness and mucus overproduction in asthma. Cadherin-26 (CDH26), a cadherin implicated in polarization of airway epithelial cells, is upregulated in asthma. However, the role of CDH26 in asthma remains unknown. We hypothesize that CDH26 plays a role in airway epitheli...

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Literature Corpus work
cfa4f4ff-00d0-50a0-b359-30165c3f42b4
DOI
10.1101/2020.12.01.20241752
Open publication

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CDH26 amplifies airway epithelial IL-4 receptor α signaling in asthmaDOI 10.1101/2020.12.01.20241752
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